A treasure trove of golf courses, the resort town of Santee near Lake Marion is an ideal getaway for a relaxed vacation. Staying in a lakeside vacation home, with your own secluded garden complete with hammocks, will naturally help you make the most of your vacation.

Choose the perfect vacation rental
Best Vacation Home Deals in Santee
Save up to 72%
Compare and find a vacation rental that fits your expectations among the 234 welcoming rentals from more than 5 vacation rental websites in Santee. By directly analyzing these accommodations, HomeToGo highlights the most economical offers as well as the most popular properties in Santee.
Top-Rated Rentals and Accommodations in Santee
Book Vacation Rental Offers with the Highest User Rating
Recommended Vacation Rentals in Santee
Find your perfect vacation rental in Santee: from $60 per night
Budget-friendly Vacation Rentals in Santee
Find Fantastic yet Inexpensive Offers
Vacation rentals and apartments with air conditioning
Keep cool during your trip to Santee and book a vacation rental with air conditioning.
Vacation rentals with Wi-Fi
Stay connected while traveling and book a Santee accommodation with high-speed internet.
Apartments and vacation rentals with a kitchen
Cook up a feast on your next vacation and book a Santee rental with full kitchen.
Popular Rental Amenities in Santee
The above filters will help you find your dream property in Santee. In Santee, 41 properties offer "Pets allowed". So, if you bring your pet everywhere, select the Pets allowed filter to compare these accommodations. It is also possible to search for an accommodation in Santee if you want a rental providing a crib as 53 of the listed properties there include "Crib."
Waterfront Vacation Rentals in Santee
Looking for an amazing beach house rental in Santee?
Use the 'distance to water' filter while searching and discover the best waterfront homes for your vacation. There is a variety of vacation rentals in Santee that are within walking distance from the coast. From pet-friendly homes by the beach to waterfront offers with hot tubs, the perfect accommodation in Santee awaits - discover it now via HomeToGo.

The Weather in Santee
You can see our climate diagram above. July is the warmest month of the year in Santee with temperatures reaching a maximum average of 91°. On the other hand, you could have temperatures dropping under 37° in January. The rainiest month is July while the driest month is October.
7-Day Weather Forecast in Santee
Accommodations for your vacation in Santee
Information about vacation rentals in Santee
🏡 Vacation rentals available | 224 homes |
---|---|
💳 Possible discounts | up to 28% |
🌙 Nightly prices starting at | $60 |
⭐ Popular amenities | Pets allowed, Fishing and Pool |
🐾 Pet friendly homes | 40 homes |
🏊 Vacation rentals with pools | 173 homes |
Frequently Asked Questions
What is the average price per night for a vacation home in Santee?
The average accommodation in Santee is priced at $60 per night. If you’re interested in a house rental, the average price is $371 per night. A apartment rental Santee will cost $610 per night on average.
How many vacation rentals are available to book in Santee?
Currently there are 224 rentals from 5 providers in Santee.
What are the most popular amenities for vacation homes in Santee?
Most travelers look for Pets allowed, Fishing, and Pool when booking a vacation rental in Santee.
How many vacation homes with a pool are in Santee?
Santee offers 173 Hotel room and Condo options available for renting.
Are pets allowed in vacation homes in Santee?
Absolutely, there are 40 vacation rentals in Santee that allow dogs , with an average nightly price of $136.
What are the best months to travel to Santee?
July and June are typically the warmest months in Santee with temperatures around 91 °F. The coldest months in Santee are January and February, with 37 °F on average.
We list offers from thousands of providers, including











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